Research Compliance

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IACUC Resources

Manual & Information

UL Lafayette IACUC Procedures Manual

IRBManager Dashboard Overview

IRBManager Tips and Tricks

IRBManager start a new IACUC application

IRBManager create an addendum or new project from approved APS

IRBManager monitor review process

IACUC Information for UL Lafayette Graduate Students

Free Power Analysis & Sample Size Software


Training for Investigators and Animal Care Staff

Training for IACUC Members

Gentle Mouse Handling


See manual above

Regulatory Agencies & Regulations

The US Department of Agriculture (USDA) upholds and enforces the Animal Welfare Act and Regulations and the USDA Animal Care Policies.  They maintain the USDA Animal Welfare Information Center where a wealth of information can be found, including searching for alternatives and the Rs, reduce, refine, replace.

The Office of Laboratory Animal Welfare (OLAW) is the agency charged with enforcing the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals that regulates animal use that is funded by the PHS.  It also provides quarterly educational webinars

PHS Policy requires institutions to utilize the principles and practices described in the Guide for the Care an Use of Laboratory Animals (the Guide).  This can be read online or a PDF can be downloaded.

Reduce, Refine, Replace, Alternatives & Euthanasia

Reduce, refine and replace is our mantra when animals are used in research.  We search for alternatives that allow us to reduce the numbers of animals or procedures per animal; refine the techniques to reduce pain; and replace the animals, when possible, with less sentient animals, computer models, simulations or cell and tissue culture.  These references are provided to assist you with your experimental design and justifications as you complete your animal procedure statement.

Replacement, Reduction and Refinement by Flecknell

Guidelines for Pain and Distress in Laboratory Animals: Responsibilities, Recognition and Alleviation

Search for Alternatives

AVMA Guidelines on Euthanasia (2020)

Administration of Substances to Laboratory Animals: Routes of Administration and Factors to Consider (2011)

Recommended Animal Care and Use Procedures from NIH

Recognition and Alleviation of Pain in Laboratory Animals

Resources for Specific Animal Classes

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Guidelines for Use of Wild Mammals in Research(2016 update)

Guidelines for the Use of Wild Birds in Research

Guidelines for the Use of Live Amphibians and Reptiles in Field Research

Guidelines for the use of Fishes in Research

Fish Sedation, Anesthesia, Analgesia and Euthanasia

Formulary for Laboratory Animals

This formulary information is provide to assist you with completing your animal procedure statement. Should you need more veterinary medical information, you are encouraged to email the Attending Vet, Dr. Dana Hasselschwert.

Abbreviations & Dose Estimation

Analgesics & Sedatives




Miscellaneous Drugs

Appendices & References